Article
Rbpj regulates development of prosensory cells in the mammalian inner ear.
Developmental biology - 15 May 2011
Yamamoto Norio, Chang Weise, Kelley Matthew W
Abstract excerpt
The vertebrate inner ear contains multiple sensory patches comprised of hair cells and supporting cells. During development these sensory patches arise from prosensory cells that are specified and maintained through the expression of specific molecular factors. Disruption of Jagged1-mediated notch signaling causes a loss of some sensory patches and disruptions in others, indicating a role in some aspect of...
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