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<i>In utero</i> adeno-associated virus (AAV)-mediated gene delivery targeting sensory and supporting cells in the embryonic mouse inner ear

2024-05-08

Abstract excerpt

In vivo gene delivery to tissues using adeno-associated vector (AAVs) has revolutionized the field of gene therapy. Yet, while sensorineural hearing loss is one of the most common sensory disorders worldwide, gene therapy applied to the human inner ear is still in its infancy. Recent advances in the development recombinant AAVs have significantly improved their cell tropism and transduction efficiency across diver...

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Literature Corpus work
1c4b5424-2931-5ac2-a5d4-5a04ae6c6f35
DOI
10.1101/2024.05.07.592885
Open publication

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