Article

Estrogen-related receptor gamma is required for normal auditory innervation and is essential for hearing

2026-05-05

Abstract excerpt

Estrogen-related receptor gamma (ESRRG), an orphan nuclear receptor with structural homology to the classical estrogen receptors, is widely recognised as a key metabolic regulator involved in mitochondrial, synaptic, and ion-homeostatic pathways. Previous clinical studies suggest a link between ESRRG and auditory function; for example, ESRRG has been associated with susceptibility to age-related hearing loss in...

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Literature Corpus work: 9803ddf2-4d30-5172-bf61-aa45dde6e485
DOI: 10.64898/2026.05.02.722410

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