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Article

Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome

1 Jan 2001

Abstract excerpt

Following the positional cloning of PDS, the gene mutated in the deafness/goitre disorder Pendred syndrome (PS), numerous studies have focused on defining the role of PDS in deafness and PS as well as elucidating the function of the PDS-encoded protein (pendrin). To facilitate these efforts and to provide a system for more detailed study of the inner-ear defects that occur in the absence of pendrin, we have...

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PMID: 11152663
DOI: 10.1093/hmg/10.2.153

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Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndromePMID 11152663Read ↗

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