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Article

Processive utilization of the human telomerase template: lack of a requirement for template switching.

The Journal of biological chemistry - 17 Dec 2004

Rivera Melissa A, Blackburn Elizabeth H

Abstract excerpt

The ribonucleoprotein telomerase is a specialized reverse transcriptase minimally composed of an RNA, TER, and a protein catalytic subunit, TERT. The TER and TERT subunits of telomerase associate to form a dimeric enzyme in several organisms, including human. A small portion of TER, the template domain, is used by telomerase for the synthesis of tandem repeats of telomeric DNA. We studied some of the requirements...

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Source

Identifiers

PMID: 15456773
DOI: 10.1074/jbc.M407768200

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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