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Article

Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility.

The EMBO journal - 15 Jan 2003

Chen Jiunn-Liang, Greider Carol W

Abstract excerpt

Telomerase contains two essential components: an RNA molecule that templates telomeric repeat synthesis and a catalytic protein component. Human telomerase is processive, while the mouse enzyme has much lower processivity. We have identified nucleotide determinants in the telomerase RNA that are...

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Identifiers

PMID: 12514136
DOI: 10.1093/emboj/cdg024
PMCID: PMC140099

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TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12514136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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