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Article

Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase.

RNA (New York, N.Y.) - 1 Sept 2005

Moriarty Tara J, Marie-Egyptienne Delphine T, Autexier Chantal

Abstract excerpt

Telomerase accurately synthesizes telomeric DNA by reverse transcription of a tightly defined template region in the telomerase RNA (TR). Reverse transcription past the 5' boundary of the template can cause the incorporation of noncognate nucleotides into telomeric DNA, which can result in disrup...

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Identifiers

PMID: 16120835
DOI: 10.1261/rna.2910105
PMCID: PMC1370828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16120835-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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