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Article

Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin.

Blood - 1 Feb 2005

Montes de Oca Rocio, Andreassen Paul R, Margossian Steven P, Gregory Richard C, Taniguchi Toshiyasu, Wang Xiaozhe, Houghtaling Scott, Grompe Markus, D'Andrea Alan D

Abstract excerpt

DNA damage activates the monoubiquitination of the Fanconi anemia (FA) protein, FANCD2, resulting in the assembly of FANCD2 nuclear foci. In the current study, we characterize structural features of FANCD2 required for this intranuclear translocation. We have previously identified 2 normal mRNA splice variants of FANCD2, one containing exon 44 sequence at the 3' end (FANCD2-44) and one containing exon 43 sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15454491
DOI: 10.1182/blood-2003-11-3997

Genes

FANCD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin.PMID 15454491Read ↗

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The identification of FANCD2 DNA binding domains reveals nuclear localization sequences.Semantic proximity Read ↗

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Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair PathwaySemantic proximity Read ↗

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