Dynamics of Fanconi anemia protein D2 in association with nuclear lipid droplet formation

Abstract excerpt

<h4>Summary</h4> Fanconi anemia (FA) is a rare genetic disease caused by the loss of function of one of the 22 associated genes and is characterized by bone marrow failure, cancer predisposition, and developmental defects. The proteins encoded by these genes (FA proteins) mainly function in DNA damage response and repair. Although FA deficiency has multiple effects on the regulation of lipid metabolism, the molec...

Topics

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• Chromosomes, Human
• Cross-Linking Reagents
• Fanconi Anemia
• Fanconi Anemia Complementation Group A Protein
• Fanconi Anemia Complementation Group D2 Protein
• Fanconi Anemia Complementation Group Proteins
• Forecasting
• Mosaicism

Identifiers and source

Literature Corpus work

d1a35b2c-3707-5bf3-94a5-a1137a636d78

DOI

10.1101/2025.02.05.636583