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Article

Mapping the genetic determinants of hypertension, metabolic diseases, and related phenotypes in the lyon hypertensive rat.

Hypertension (Dallas, Tex. : 1979) - 1 Nov 2004

Bilusic Marijo, Bataillard Alain, Tschannen Michael R, Gao Li, Barreto Nadia E, Vincent Madeleine, Wang Tao, Jacob Howard J, Sassard Jean, Kwitek Anne E

Abstract excerpt

The complex nature of hypertension makes identifying the pathophysiology and its genetic contributions a challenging task. One powerful approach for the genetic dissection of blood pressure regulation is studying inbred rat models of hypertension, as they provide natural allele variants but reduced heterogeneity (both genetic and etiologic). Furthermore, the detailed physiologic studies to which the rat is...

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PMID: 15452030
DOI: 10.1161/01.HYP.0000144542.57306.5e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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