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Article

Genomic structure of nucleotide diversity among Lyon rat models of metabolic syndrome.

BMC genomics - 14 Mar 2014

Ma Man Chun John, Atanur Santosh S, Aitman Timothy J, Kwitek Anne E

Abstract excerpt

BACKGROUND: The metabolic syndrome (MetS), a complex disorder involving hypertension, obesity, dyslipidemia and insulin resistance, is a major risk factor for heart disease, stroke, and diabetes. The Lyon Hypertensive (LH), Lyon Normotensive (LN) and Lyon Low-pressure (LL) rats are inbred strains simultaneously derived from a common outbred Sprague Dawley colony by selection for high, normal, and low blood...

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PMID: 24628878
DOI: 10.1186/1471-2164-15-197
PMCID: PMC4003853

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