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Article

The human T locus and spina bifida risk.

Human genetics - 1 Nov 2004

Jensen Liselotte E, Barbaux Sandrine, Hoess Katy, Fraterman Sven, Whitehead Alexander S, Mitchell Laura E

Abstract excerpt

The transcription factor T is essential for mesoderm formation and axial development during embryogenesis. Embryonic genotype for a single-nucleotide polymorphism in intron 7 of T ( TIVS7 T/C) has been associated with the risk of spina bifida in some but not all studies. We developed a novel genotyping assay for the TIVS7 polymorphism using heteroduplex generator methodology. This assay was used to genotype spina...

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Identifiers

PMID: 15449172
DOI: 10.1007/s00439-004-1185-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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