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Article

The 894G>T variant in the endothelial nitric oxide synthase gene and spina bifida risk.

Journal of human genetics - 1 Jan 2007

van der Linden Ivon J M, Heil Sandra G, den Heijer Martin, Blom Henk J

Abstract excerpt

The 894G>T single nucleotide polymorphism (SNP) in the endothelial NOS (NOS3) gene, has recently been associated with embryonic spina bifida risk. In this study, a possible association between the NOS3 894G>T SNP and spina bifida risk in both mothers and children in a Dutch population was examined using both a case-control design and a transmission disequilibrium test (TDT). Possible interactions between the NOS3...

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Source

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Identifiers

PMID: 17479212
DOI: 10.1007/s10038-007-0147-0
PMCID: PMC1915643

Genes

NOS3
MTHFR

Provenance

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The 894G>T variant in the endothelial nitric oxide synthase gene and spina bifida risk.PMID 17479212Read ↗

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