Differences in the contribution of HLA-DR and -DQ haplotypes to susceptibility to adult- and childhood-onset type 1 diabetes in Japanese patients.

doi:10.2337/diabetes.53.10.2684

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Article

Differences in the contribution of HLA-DR and -DQ haplotypes to susceptibility to adult- and childhood-onset type 1 diabetes in Japanese patients.

Diabetes - 1 Oct 2004

Murao Satoshi, Makino Hideichi, Kaino Yukikazu, Konoue Etsushi, Ohashi Jun, Kida Kaichi, Fujii Yasuhisa, Shimizu Ikki, Kawasaki Eiji, Fujiyama Masao, Kondo Shiori, Tanaka Kiyonobu, Tarumi Yoshinao, Seto Isamu, Kato Kenichi, Ohno Keizo, Kusunoki Yukiko, Ebisui Osamu, Takada Yasuharu, Tanabe Katsuya, Takemoto Koji, Onuma Hiroshi, Nishimiya Tatsuya, Osawa Haruhiko

Abstract excerpt

To clarify heterogeneity in Japanese adult-onset type 1 diabetes, we analyzed the HLA-DR and -DQ haplotypes, depending on the clinical phenotype, and compared them with those in childhood-onset type 1 diabetes (CO). The patients in a previously reported Ehime Study were divided into subgroups by the mode of onset of diabetes: 68 acute-onset type 1 diabetic patients (AO) and 28 slowly progressive type 1 diabetic...

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PMID: 15448101
DOI: 10.2337/diabetes.53.10.2684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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