Article
Effect of human leukocyte antigen class II genes on acute-onset and slow-onset type 1 diabetes in the Japanese population.
Human immunology - 1 Aug 2010
Katahira Masahito, Segawa Satoko, Maeda Harumi, Yasuda Yoshinori
Abstract excerpt
The contribution of the human leukocyte antigen (HLA) subtype to slow-onset type 1 diabetes (T1D), which includes latent autoimmune diabetes in adults (LADA), remains unclear in the Japanese population. We compared the frequencies of HLA DR-DQ haplotypes and genotypes of 72 acute-onset T1D patients, 100 slow-onset T1D patients, and 292 control subjects. The frequencies of DRB1*0405-DQB1*0401 (DR4) and...
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