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Adult-onset type 1 diabetic patients with less severe clinical manifestation have less risk DR-DQ genotypes than childhood-onset patients.

Diabetes/metabolism research and reviews - 1 Jan 2021

Ren Wenqian, Yang Daizhi, Jiang Ziyu, Xian Yingxin, Huang Qianwen, Luo Sihui, Zheng Xueying, Yan Jinhua, Xu Wen, Yao Bin, Wang Cong-Yi, Bei Jin-Xin, Groop Leif, Noble Janelle A, Weng Jianping

Abstract excerpt

BACKGROUND: The aim of this study was to investigate differences in clinical features and HLA genotypes between adult-onset and childhood-onset patients with type 1 diabetes in a Chinese population. MATERIALS AND METHODS: This study enrolled 716 Han Chinese patients with type 1 diabetes from Guangdong (258 childhood-onset and 458 adult-onset) to compare their clinical features. Of them 214 patients with classical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32463555
DOI: 10.1002/dmrr.3357

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