Article
Slowly progressing form of type 1 diabetes mellitus in children: genetic analysis compared with other forms of diabetes mellitus in Japanese children.
Pediatric diabetes - 1 Dec 2005
Ohtsu Shigeyuki, Takubo Noriyuki, Kazahari Mayumi, Nomoto Keiko, Yokota Fumiyuki, Kikuchi Nobuyuki, Koike Akemi, Matsuura Nobuo
Abstract excerpt
AIMS: Slowly progressing insulin-dependent diabetes mellitus (SPIDDM, hereafter referred to as IDDMS in this article) is a unique subtype of type 1 diabetes in Japanese children. To clarify the genetic background of IDDMS, we analyzed HLA-DRB1, -DQB1 and -DQA1 alleles, phenotypes, and genotypes and compared them with acute-onset type 1 diabetes, non-insulin-dependent diabetes mellitus (NIDDM), and control...
Topics
- Age of Onset
- Arginine
- Asian People
- Aspartic Acid
- Autoantibodies
- Case-Control Studies
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Female
- Gene Frequency