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Article

Optimal haplotype structure for linkage disequilibrium-based fine mapping of quantitative trait loci using identity by descent.

Genetics - 1 Mar 2006

Grapes L, Firat M Z, Dekkers J C M, Rothschild M F, Fernando R L

Abstract excerpt

A linkage disequilibrium-based method for fine mapping quantitative trait loci (QTL) has been described that uses similarity between individuals' marker haplotypes to determine if QTL alleles are identical by descent (IBD) to model covariances among individuals' QTL alleles for a mixed linear model. Mapping accuracy with this method was found to be sensitive to the number of linked markers that was included in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16322505
DOI: 10.1534/genetics.105.048686
PMCID: PMC1456285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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