Article
Deep Transcriptome Profiling of Multiple Myeloma Using Quantitative Phenotypes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2023
Griffin Rosalie, Hanson Heidi A, Avery Brian J, Madsen Michael J, Sborov Douglas W, Camp Nicola J
Abstract excerpt
BACKGROUND: Transcriptome studies are gaining momentum in genomic epidemiology, and the need to incorporate these data in multivariable models alongside other risk factors brings demands for new approaches. METHODS: Here we describe SPECTRA, an approach to derive quantitative variables that capture the intrinsic variation in gene expression of a tissue type. We applied the SPECTRA approach to bulk RNA sequencing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.