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Article

Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes.

Antimicrobial agents and chemotherapy - 1 Oct 2004

Hallett Rachel L, Sutherland Colin J, Alexander Neal, Ord Rosalynn, Jawara Musa, Drakeley Chris J, Pinder Margaret, Walraven Gijs, Targett Geoffrey A T, Alloueche Ali

Abstract excerpt

Malaria parasites carrying genes conferring resistance to antimalarials are thought to have a selective advantage which leads to higher rates of transmissibility from the drug-treated host. This is a likely mechanism for the increasing prevalence of parasites with resistance to chloroquine (CQ) and sulfadoxine-pyrimethamine in sub-Saharan Africa. Combination therapy is the key strategy being implemented to reduce...

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Source

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Identifiers

PMID: 15388456
DOI: 10.1128/AAC.48.10.3940-3943.2004
PMCID: PMC521891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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