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Article

The interplay between drug resistance and fitness in malaria parasites

31 Jul 2013

Abstract excerpt

Controlling the spread of antimalarial drug resistance, especially resistance of Plasmodium falciparum to artemisinin-based combination therapies, is a high priority. Available data indicate that, as with other microorganisms, the spread of drug-resistant malaria parasites is limited by fitness costs that frequently accompany resistance. Resistance-mediating polymorphisms in malaria parasites have been identified...

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PMID: 23899091
DOI: 10.1111/mmi.12349

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