Article
Impaired fitness of drug-resistant malaria parasites: evidence and implication on drug-deployment policies.
Expert review of anti-infective therapy - 1 Jun 2009
Babiker Hamza A, Hastings Ian M, Swedberg Göte
Abstract excerpt
Malaria, a leading parasitic disease, inflicts an enormous toll on human lives and is caused by protozoal parasites belonging to the genus Plasmodium. Antimalarial drugs targeting essential biochemical processes in the parasite are the primary resources for management and control. However, the parasite has established mutations, substantially reducing the efficacy of these drugs. First-line therapy is faced the...
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