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Article

Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria.

Breast cancer (Tokyo, Japan) - 1 Jan 2013

Lajin Bassam, Hamzeh Abdul Rezzak, Ghabreau Lina, Mohamed Ali, Al Moustafa Ala-Eddin, Alachkar Amal

Abstract excerpt

BACKGROUND: Catechol-O-methyltransferase (COMT) inactivates catechol estrogens by methylation and thus may play a protective role against mutations induced by estrogen metabolites. In this study we investigated the relationship between the Vall58Met polymorphism in the COMT gene and breast cancer risk in a population-based case control study in Syria. METHODS: We examined 135 breast cancer patients and 107...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22124994
DOI: 10.1007/s12282-011-0309-y

Genes

COMT

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Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer risk: a case control study in Syria.PMID 22124994Read ↗

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Association between the COMT Val158Met polymorphism and breast cancer risk: a meta-analysis of 30,199 cases and 38,922 controls.Semantic proximity Read ↗

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