Insulin-like growth factor-I gene polymorphism and breast cancer risk in Chinese women.

doi:10.1002/ijc.20571

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Article

Insulin-like growth factor-I gene polymorphism and breast cancer risk in Chinese women.

International journal of cancer - 10 Jan 2005

Wen Wanqing, Gao Yu-Tang, Shu Xiao-Ou, Yu Herbert, Cai Qiuyin, Smith Jeffrey R, Zheng Wei

Abstract excerpt

The evidence that high circulating levels of insulin-like growth factor-I (IGF-I) are associated with an increased risk of breast cancer among premenopausal women lends credence to the hypothesis that genetic polymorphisms in the IGF-I gene may be involved in the disease. A population-based case-control study was conducted to assess the association of IGF-I gene polymorphisms [(CA)n repeats in the promoter...

Topics

Adult
Breast Neoplasms
Case-Control Studies
China
Female
Genetic Predisposition to Disease
Genotype
Humans
Insulin-Like Growth Factor I
Middle Aged
Odds Ratio
Polymorphism, Genetic
Premenopause
Promoter Regions, Genetic
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 15386404
DOI: 10.1002/ijc.20571

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