Article
Differential effects of insulin-like growth factor-1 CA repeat polymorphism on breast cancer risk along with race: a meta-analysis.
Gene - 1 Aug 2013
He Bangshun, Xu Yeqiong, Pan Yuqin, Li Rui, Gao Tianyi, Song Guoqi, Gu Ling, Nie Zhenlin, Chen Liping, Wang Shukui
Abstract excerpt
BACKGROUND: Insulin-like growth factor (IGF)-I has been implicated in processes leading to breast cancer initiation and progression. A CA repeat polymorphism in the promoter region of IGF-I may suppress transcriptional activity and be associated with risk of breast cancer. A variety of case-control studies have been published evaluating the association between IGF1 CA repeat polymorphism and breast cancer....
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