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Article

A sequence repeat in the insulin-like growth factor-1 gene and risk of breast cancer.

International journal of cancer - 20 Jul 2002

Missmer Stacey A, Haiman Christopher A, Hunter David J, Willett Walter C, Colditz Graham A, Speizer Frank E, Pollak Michael N, Hankinson Susan E

Abstract excerpt

Insulin-like growth factor-1 (IGF-I), a potent mitogen, is hypothesized to influence breast cancer risk. In 3 previous studies, a polymorphism in the IGF-1 gene (sequence repeat length) was associated with plasma IGF-I level. We evaluated prospectively the relationships among a (CA)(n) repeat polymorphism in the IGF-1 gene, IGF-I level and breast cancer risk in a nested case-control study conducted within the...

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Identifiers

PMID: 12115549
DOI: 10.1002/ijc.10473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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