Article
IGF-I (CA) repeat polymorphisms and risk of cancer: a meta-analysis.
Journal of human genetics - 1 Jan 2008
Chen Xin, Guan Jianming, Song Yuting, Chen Peilin, Zheng Hongxia, Tang Cheng, Wu Qihan
Abstract excerpt
Insulin-like growth factor-I modulates cell growth and survival, and is thought to be important in tumor development. A (CA)19 repeat polymorphism in the promoter region of IGF-I gene that may affect transcription activity has been implicated as a risk factor for cancer, but individual studies have been inconclusive or controversial. Therefore, we performed a meta-analysis of 17 studies with IGF-I (CA)19 repeat...
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