Article
Association between aminolevulinate dehydrase genotypes and blood lead levels in children from a lead-contaminated area in Antofagasta, Chile.
Archives of environmental contamination and toxicology - 1 Aug 2004
Pérez-Bravo F, Ruz M, Morán-Jiménez M J, Olivares M, Rebolledo A, Codoceo J, Sepúlveda V, Jenkin A, Santos J L, Fontanellas A
Abstract excerpt
Childhood environmental lead exposure in the city of Antofagasta, Chile, was generated by the accumulation of recently removed lead stores derived from mining activities for a long period of time. Susceptibility to harmful lead effects may be associated with polymorphisms of delta-aminolevulinic acid dehydratase (ALAD) because of the differential binding of lead to the codified proteins. We assessed the...
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