Article
Maternal Δ-aminolevulinic acid dehydratase 1-2 genotype enhances fetal lead exposure and increases the susceptibility to the development of cerebral palsy.
Environmental science and pollution research international - 1 Dec 2020
Abdel Hamid Omaima Ibrahim, Khayal Eman El-Sayed Hassan, Tolba Sabry Abdel Rahman, Orabi Eman Elshahat
Abstract excerpt
Limited epidemiologic studies questioned the association between pre- and postnatal lead exposure and the development of cerebral palsy (CP). Moreover, the genotypes of δ-aminolevulinic acid dehydratase (δ-ALAD) in CP patients and their mothers and their association to the blood lead levels (BLLs) were not previously studied. This study aimed to evaluate the association between δ-ALAD gene polymorphism and BLL in...
Topics
- Case-Control Studies
- Cerebral Palsy
- Child
- Female
- Genotype
- Humans
- Lead
- Porphobilinogen Synthase
- Pregnancy
