Article
Genetic Polymorphism of Delta Aminolevulinic Acid Dehydratase (ALAD) Gene and Symptoms of Chronic Mercury Exposure in Munduruku Indigenous Children within the Brazilian Amazon.
International journal of environmental research and public health - 19 Aug 2021
Perini Jamila Alessandra, Silva Mayara Calixto, Vasconcellos Ana Claudia Santiago de, Viana Paulo Victor Sousa, Lima Marcelo Oliveira, Jesus Iracina Maura, Kempton Joseph William, Oliveira Rogério Adas Ayres, Hacon Sandra Souza, Basta Paulo Cesar
Abstract excerpt
Genetic polymorphisms involved in mercury toxicokinetics and toxicodynamics may be associated with severe mercury toxicity. This study aimed to investigate the impact of an ALAD polymorphism on chronic mercury exposure and the health situation of indigenous children from the Brazilian Amazon. One-hundred-and-three indigenous children (under 15 years old) were included and genotyped (rs1800435) using a TaqMan...
Topics
- Animals
- Child
- Child, Preschool
- Female
- Gene Frequency
- Genotype
- Humans