Article
Fine mapping of the 11q22-23 tumor suppressive region and involvement of TSLC1 in nasopharyngeal carcinoma.
International journal of cancer - 20 Nov 2004
Lung Hong Lok, Cheng Yue, Kumaran Mande Kuppusamy, Liu Edison Tak-Bun, Murakami Yoshinori, Chan Cheuk Yu, Yau Wing Lung, Ko Josephine Mun Yee, Stanbridge Eric J, Lung Maria Li
Abstract excerpt
Previous studies transferring an intact chromosome 11 into HONE1 cells demonstrated the functional significance of chromosome regions, 11q13 and 11q22-23, in nasopharyngeal carcinoma (NPC) development. In our study the 11q22-23 region was comprehensively re-investigated by detailed microsatellite and single nucleotide polymorphism genotyping and by fluorescence in situ hybridization to map precisely the regions...
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