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Article

Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinoma.

Cancer - 1 Apr 2002

Ko Jenq-Yuh, Lee Tso-Ching, Hsiao Chin-Fu, Lin Guan-Lu, Yen Sang-Hue, Chen Kuang Y, Hsiung Chao A, Chen Pei-Jer, Hsu Mow-Ming, Jou Yuh-Shan

Abstract excerpt

BACKGROUND: Recurrent deletion on a chromosomal location in tumor cells can be detected by frequent allelic loss and generally is considered to be an indication of the existence of a tumor suppressor gene (TSG) in the region. In the current study, using fluorescent-labeled, high-density microsatellite markers for allelotyping, the authors pinpointed three minimal deleted regions (MDRs) and screened mutations of...

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Identifiers

PMID: 11932901
DOI: 10.1002/cncr.10406

Genes

FHIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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