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Article

Localization of tumor suppressor activity important in nonsmall cell lung carcinoma on chromosome 11q

7 Jul 1998

Abstract excerpt

Loss of heterozygosity on chromosome 11q23 is observed at high frequency in human nonsmall cell lung carcinomas (NSCLCs), suggesting the presence of a tumor suppressor gene. Previous analysis of DNA from 79 patients identified a commonly deleted segment of 5 centimorgans. Complementation analysis was used to further localize a putative tumor suppressor gene. Three yeast artificial chromosome (YAC) clones spanning...

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Identifiers

PMID: 9653156
DOI: 10.1073/pnas.95.14.8153

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Localization of tumor suppressor activity important in nonsmall cell lung carcinoma on chromosome 11qPMID 9653156Read ↗

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