Article
Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches.
Seminars in cancer biology - 1 Apr 2012
Lo Kwok-Wai, Chung Grace Tin-Yun, To Ka-Fai
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is consistently associated with EBV infection and prevalence in southern China and Southeast Asia. In addition to EBV, the development of NPC involves cumulative genetic and epigenetic changes influenced by predisposing genetic factors and environmental carcinogens. Over the past two decades, knowledge of genetic and epigenetic alterations of NPC has rapidly accumulated. Multiple...
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