A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma.

doi:10.1158/0008-5472.can-03-3253

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A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma.

Cancer research - 15 Mar 2004

Xiong Wei, Zeng Zhao Yang, Xia Jia Hui, Xia Kun, Shen Shou Rong, Li Xiao Ling, Hu Dong Xu, Tan Chen, Xiang Juan Juan, Zhou Jie, Deng Hao, Fan Song Qing, Li Wei Fang, Wang Rong, Zhou Ming, Zhu Shi Guo, Lü Hong Bin, Qian Jun, Zhang Bi Cheng, Wang Jie Ru, Ma Jian, Xiao Bing Yi, Huang He, Zhang Qiu Hong, Zhou Yan Hong, Luo Xiao Min, Zhou Hou De, Yang Yi Xin, Dai He Ping, Feng Guo Yin, Pan Qian, Wu Ling Qian, He Lin, Li Gui Yuan

Abstract excerpt

Nasopharyngeal carcinoma (NPC) poses one of the serious health problems in southern Chinese, with an incidence rate ranging from 15 to 50/100,000. Chromosome translocation t(1;3) and frequent loss of heterogeneity on short arms of chromosome 3 and 9 have been reported to be associated with NPC, and a genome-wide scan identified an NPC susceptibility locus on chromosome 4p15.1-q12 recently. In our study, we...

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PMID: 15026332
DOI: 10.1158/0008-5472.can-03-3253

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