Demonstration of a testis-specific trans-acting factor Tet-1 in vitro that binds to the promoter of the mouse protamine 1 gene.

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Article

Demonstration of a testis-specific trans-acting factor Tet-1 in vitro that binds to the promoter of the mouse protamine 1 gene.

The Journal of biological chemistry - 5 Mar 1992

Tamura T, Makino Y, Mikoshiba K, Muramatsu M

Abstract excerpt

We have established testis-specific in vitro transcription of the mouse protamine 1 (MP1) gene using rat testis nuclear extracts. Addition of testis nuclear extracts to brain extracts enhanced transcription from the MP1 upstream sequence-carrying adenovirus major late promoter. Moreover, the MP1 upstream region from positions -92 to -41 alone exhibited transcriptional activation in a tissue-specific manner. DNase...

Topics

Adenoviridae
Animals
Base Sequence
DNA
DNA Fingerprinting
DNA-Binding Proteins
Female
Gene Expression Regulation
Genes, Viral
Male
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Plasmids

Promoter Regions, Genetic

Protamines

Substrate Specificity

Testis

Source

Open in PubMed

Identifiers

PMID: 1537824

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1537824-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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