Article
Binding of a CTF/NF1-like protein to the mouse colony-stimulating factor-1 gene promoter.
DNA and cell biology - 1 Nov 1995
Konicek B W, Xia X L, Harrington M A
Abstract excerpt
Circulating and tissue-specific monocytes/macrophages, through production of hydrolytic enzymes and growth factors, can dramatically affect the local tissue environment. Colony-stimulating factor-1 (CSF-1) is a key regulator of monocyte/macrophage cell activity. CSF-1 is produced by stromal elements, including fibroblasts, which are found in all tissues. To understand at the molecular level how changes in CSF-1...
Topics
- Animals
- Base Sequence
- Binding, Competitive
- CCAAT-Enhancer-Binding Proteins
- Cell Line
- Chloramphenicol O-Acetyltransferase
- DNA
- DNA-Binding Proteins
- Fibroblasts
- Macrophage Colony-Stimulating Factor
- Mice
