Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition.

doi:10.1186/1471-2156-6-21

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Article

Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition.

BMC genetics - 25 Apr 2005

Zeggini Eleftheria, Barton Anne, Eyre Stephen, Ward Daniel, Ollier William, Worthington Jane, John Sally

Abstract excerpt

BACKGROUND: The selection of markers in association studies can be informed through the use of haplotype blocks. Recent reports have determined the genomic architecture of chromosomal segments through different haplotype block definitions based on linkage disequilibrium (LD) measures or haplotype...

Topics

Chromosomes, Human, Pair 17
Gene Frequency
Genetic Markers
Genome, Human
Genomics
Haplotypes
Humans
Polymorphism, Single Nucleotide
United Kingdom

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