Article
Finding haplotype block boundaries by using the minimum-description-length principle.
American journal of human genetics - 1 Aug 2003
Anderson Eric C, Novembre John
Abstract excerpt
We present a method for detecting haplotype blocks that simultaneously uses information about linkage-disequilibrium decay between the blocks and the diversity of haplotypes within the blocks. By use of phased single-nucleotide polymorphism data, our method partitions a chromosome into a series of adjacent, nonoverlapping blocks. The partition is made by choosing among a family of Markov models for block...
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