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Article

Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth.

Genes & development - 15 Sept 2004

Hipfner David R, Keller Nadine, Cohen Stephen M

Abstract excerpt

The Drosophila Sterile-20 kinase Slik promotes tissue growth during development by stimulating cell proliferation and by preventing apoptosis. Proliferation within an epithelial sheet requires dynamic control of cellular architecture. Epithelial integrity fails in slik mutant imaginal discs. Cells leave the epithelium and undergo apoptosis. The abnormal behavior of slik mutant cells is due to failure to...

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Identifiers

PMID: 15371338
DOI: 10.1101/gad.303304
PMCID: PMC517517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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