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Article

Association of HPC2/ELAC2 genotypes and prostate cancer.

American journal of human genetics - 1 Oct 2000

Rebbeck T R, Walker A H, Zeigler-Johnson C, Weisburg S, Martin A M, Nathanson K L, Wein A J, Malkowicz S B

Abstract excerpt

HPC2/ELAC2 has been identified as a prostate cancer (CaP) susceptibility gene. Two common missense variants in HPC2/ELAC2 have been identified: a Ser-->Leu change at amino acid 217, and an Ala-->Thr change at amino acid 541. Tavtigian et al. reported that these variants were associated with CaP in a sample of men drawn from families with hereditary CaP. To confirm this report in a sample unselected for family...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10986046
DOI: 10.1086/303096
PMCID: PMC1287872

Genes

ELAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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