Article
Ser217Leu polymorphism of the HPC2/ELAC2 gene associated with prostatic cancer risk in Japanese men.
International journal of cancer - 1 Nov 2003
Takahashi Hiroyuki, Lu Wei, Watanabe Masatoshi, Katoh Takahiko, Furusato Masakuni, Tsukino Hiromasa, Nakao Hiroyuki, Sudo Akemi, Suzuki Hiroyoshi, Akakura Koichiro, Ikemoto Isao, Asano Kouji, Ito Takaaki, Wakui Shin, Muto Tomoko, Hano Hiroshi
Abstract excerpt
The HPC2/ELAC2 gene may be associated with hereditary/familial prostate cancer (PCa). Two common missense variants (Ser217Leu and Ala541Thr) have been reported in the gene. We performed mutational, allelotyping and expression analyses and a molecular epidemiological study to clarify the relations...
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