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Article

ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.

Journal of the National Cancer Institute - 4 Jun 2003

Severi Gianluca, Giles Graham G, Southey Melissa C, Tesoriero Andrea, Tilley Wayne, Neufing Petra, Morris Howard, English Dallas R, McCredie Margaret R E, Boyle Peter, Hopper John L

Abstract excerpt

BACKGROUND: The ELAC2 gene has been proposed to be a prostate cancer susceptibility gene and is being referred to as HPC2, in part because three case-control studies suggested that two common polymorphisms (Ser217Leu and Ala541Thr) are associated with risk. However, four subsequent larger studies have not confirmed this association. In five of the seven total studies, subject selection was influenced by...

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Identifiers

PMID: 12783937
DOI: 10.1093/jnci/95.11.818

Genes

ELAC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.PMID 12783937Read ↗

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HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease.Semantic proximity Read ↗

Association of common missense changes in ELAC2 ( HPC2) with prostate cancer in a Japanese case-control series.Semantic proximity Read ↗

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