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Article

Role of genomic DNA methylation in detection of cytologic and histologic abnormalities in high risk HPV-infected women

4 Jan 2019

Abstract excerpt

Cervical cancer is the fourth most common malignancy affecting women worldwide. The development of disease is related to high-risk human papillomavirus (hrHPV) infection. Cytology has been the most recommended triage for primary cervical (pre)cancer screening despite relatively low sensitivity. Recently, genomic DNA methylation has been proposed as an additional marker to increase sensitivity for detecting...

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PMID: 30608989
DOI: 10.1371/journal.pone.0210289

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