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Article

Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia

30 Sept 2012

Abstract excerpt

Epigenetic modifications, such as aberrant DNA promoter methylation, are frequently observed in cervical cancer. Identification of hypermethylated regions allowing discrimination between normal cervical epithelium and high-grade cervical intraepithelial neoplasia (CIN2/3), or worse, may improve current cervical cancer population-based screening programs. In this study, the DNA methylome of high-grade CIN lesions...

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Share to Cancer-related gene regulation
Share to Cervical Cancer and HPV Research
Share to Epigenetics and DNA Methylation

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PMID: 23018867
DOI: 10.4161/epi.22301

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