Article
Aberrant gene-specific DNA methylation signature analysis in cervical cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2017
Bhat Samatha, Kabekkodu Shama Prasada, Varghese Vinay Koshy, Chakrabarty Sanjiban, Mallya Sandeep P, Rotti Harish, Pandey Deeksha, Kushtagi Pralhad, Satyamoorthy Kapaettu
Abstract excerpt
Multicomponent molecular modifications such as DNA methylation may offer sensitive and specific cervical intraepithelial neoplasia and cervical cancer biomarkers. In this study, we tested cervical tissues at various stages of tumor progression for 5-methylcytosine and 5-hydroxymethylcytosine levels and also DNA promoter methylation profile of a panel of genes for its diagnostic potential. In total,...
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