Article
SAM domains can utilize similar surfaces for the formation of polymers and closed oligomers.
Journal of molecular biology - 1 Oct 2004
Ramachander Ranjini, Bowie James U
Abstract excerpt
The mitogen-activated protein kinase (MAPK) Byr2 and its activator Ste4 are involved in the mating pheromone response pathway of Schizosaccharomyces pombe and interact via their SAM domains. SAM domains can self-associate to form higher-order structures, including dimers, polymers and closed oligomers. Ste4-SAM is adjacent to a trimeric leucine zipper domain and we have shown previously that the two domains...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
