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Article

The solution structure of the S.cerevisiae Ste11 MAPKKK SAM domain and its partnership with Ste50.

Journal of molecular biology - 10 Sept 2004

Kwan Jamie J, Warner Neil, Pawson Tony, Donaldson Logan W

Abstract excerpt

Ste11 is a MAPKKK from Saccharomyces cerevisiae that helps mediate the response to mating pheromone and the ability to thrive in high-salt environments. These diverse functions are facilitated by a direct interaction between the SAM domain of Ste11 with the SAM domain of its regulatory partner, Ste50. We have solved the NMR structure of the Ste11 SAM domain (PDB 1OW5), which reveals a compact, five alpha-helix...

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Source

Identifiers

PMID: 15327964
DOI: 10.1016/j.jmb.2004.06.064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The solution structure of the S.cerevisiae Ste11 MAPKKK SAM domain and its partnership with Ste50.PMID 15327964Read ↗

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