Article
Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe.
Molecular and cellular biology - 1 Oct 1996
Barr M M, Tu H, Van Aelst L, Wigler M
Abstract excerpt
A conserved MAP kinase cascade is central to signal transduction in both simple and complex eukaryotes. In the yeast Schizosaccharomyces pombe, Byr2, a homolog of mammalian MAPK/ERK kinase kinase and Saccharomyces cerevisiae STE11, is required for pheromone-induced sexual differentiation. A screen for S. pombe proteins that interact with Byr2 in a two-hybrid system led to the isolation of Ste4, a protein that is...
Topics
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- Crosses, Genetic
- DNA Primers
- Fungal Proteins
- GTP-Binding Protein beta Subunits
- GTP-Binding Proteins
- Genotype
- Heterotrimeric GTP-Binding Proteins
- Leucine Zippers