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Article

Structural basis for diversity in the SAM clan of riboswitches.

Proceedings of the National Academy of Sciences of the United States of America - 6 May 2014

Trausch Jeremiah J, Xu Zhenjiang, Edwards Andrea L, Reyes Francis E, Ross Phillip E, Knight Rob, Batey Robert T

Abstract excerpt

In bacteria, sulfur metabolism is regulated in part by seven known families of riboswitches that bind S-adenosyl-l-methionine (SAM). Direct binding of SAM to these mRNA regulatory elements governs a downstream secondary structural switch that communicates with the transcriptional and/or translational expression machinery. The most widely distributed SAM-binding riboswitches belong to the SAM clan, comprising...

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Identifiers

PMID: 24753586
DOI: 10.1073/pnas.1312918111
PMCID: PMC4020084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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